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3 de ago. de 2022 · Cellular senescence regulates physiological and homeostatic processes, particularly during embryonic development and wound healing, but can also be a pathological process that contributes...
16 de dic. de 2020 · Cellular senescence occurs in response to many different triggers, including DNA damage, telomere dysfunction, oncogene activation and organelle stress, and has been linked to processes such as...
- Raffaella Di Micco, Valery Krizhanovsky, Darren Baker, Fabrizio d’Adda di Fagagna
- 2021
25 de nov. de 2021 · Cellular senescence is a complex and multistep biological process which cells can undergo in response to different stresses. Referring to a highly stable cell cycle arrest, cellular senescence can influence a multitude of biological processes—both physiologically and pathologically.
- 10.3390/biomedicines9121769
- 2021/12
- Biomedicines. 2021 Dec; 9(12): 1769.
29 de mar. de 2021 · Cellular senescence is a stable cell cycle arrest that can be triggered in normal cells in response to various intrinsic and extrinsic stimuli, as well as developmental signals.
- Ruchi Kumari, Parmjit Jat
- 10.3389/fcell.2021.645593
- 2021
- Front Cell Dev Biol. 2021; 9: 645593.
Cellular senescence is a cell state implicated in various physiological processes and a wide spectrum of age-related diseases. Recently, interest in therapeutically targeting senescence to improve healthy aging and age-related disease, otherwise known as senotherapy, has been growing rapidly.
- Vassilis Gorgoulis, Peter D. Adams, Andrea Alimonti, Dorothy C. Bennett, Oliver Bischof, Cleo Bishop...
- 2019
23 de may. de 2022 · Here, we describe the mechanisms, markers and biological functions of cellular senescence. We primarily focus on the concept of heterogeneity and its consequences for the identification and therapeutic targeting of senescent cells.
16 de dic. de 2020 · Cellular senescence occurs in response to many differ-ent triggers, including DNA damage, telomere dysfunc-tion, oncogene activation and organelle stress, and has been linked to processes such...
