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  1. Figure 5.1.1 – Layers of Skin: The skin is composed of two main layers: the epidermis, made of closely packed epithelial cells, and the dermis, made of dense, irregular connective tissue that houses blood vessels, hair follicles, sweat glands, and other structures.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
    • Stratum Basale
    • Stratum spinosum
    • Stratum granulosum
    • Stratum Lucidum
    • Stratum Corneum
    • Mnemonic

    ​Stratum basale acts as the stem cell region for the epidermis. It consists of a mixture of simple cuboidal to columnar epithelium resting on a basement membrane. Compared to the cytoplasm, the nuclei of these cells are large, euchromatic, with prominent nucleoli giving a marked basophiliato this layer. The basement membrane serves as the point of ...

    Most of the cells ascending from the stratum basale to enter the stratum spinosum are post-mitotic cells and are committed to becoming mature keratinocytes. However, there are a few stem cells in the basal region of the stratum spinosum that contribute to ascending progeny that replenish exfoliated cells of the superficial layers. There are approxi...

    During the upward migration from the stratum spinosum, the cells of the stratum granulosum become flattened polygonal and form two to three layers of pyknoticcells. Recall that pyknosis is a characteristic feature of apoptosis (and necrosis) in which the nuclear material condenses. Karyorrhexis (disintegration of the nucleus) subsequently ensues. T...

    The stratum lucidum is an epidermal layer only appreciated in glabrous skin. Here, a translucent layer of cells lie above the stratum granulosum and below the stratum corneum. The cells are filled with keratin filamentsand are devoid of nuclei and organelles.

    Finally, the stratum corneum is the most superficial layer of the skin. It is designed to withstand repetitive insults in order to protect the deeper structures. The cells of this 15-20 layered stratum are dead, non nucleated, filled with soft keratin filaments, and referred to as squames(owing to their flattened appearance). There is considerable ...

    If remembering all these layers seems like a daunting prospective a mnemonic can help! Just memorise 'British & Spanish GranniesLove Cornflakes', which covers the following structures: 1. Stratum Basale 2. Stratum Spinosum 3. Stratum Granulosum 4. Stratum Lucidum 5. Stratum Corneum

  2. 19 de may. de 2023 · The number of skin layers that exists depends on how you count them. You have three main layers of skin—the epidermis, dermis, and hypodermis (subcutaneous tissue). Within these layers are additional layers. If you count the layers within the layers, the skin has eight or even 10 layers.

  3. 5 de ene. de 2018 · The Layers of Your Skin. Your skin includes three layers known as epidermis, dermis, and fat. Some health issues, such as dermatitis and infections, can affect how these different layers work to...

  4. 4 de oct. de 2019 · Reviewed by: BD Editors. Last Updated: October 4, 2019. Skin Definition. Skin is the soft outer tissue which covers vertebrates. In humans, it is the body’s largest organ, covering a total area of about 20 square feet.

  5. Facts about the skin. The skin is the body's largest organ. It covers the entire body. It serves as a protective shield against heat, light, injury, and infection. The skin also: Regulates body temperature. Stores water and fat. Is a sensory organ. Prevents water loss.

  6. 14 de nov. de 2022 · Skin is the largest organ in the body and covers the body's entire external surface. It is made up of three layers, the epidermis, dermis, and the hypodermis, all three of which vary significantly in their anatomy and function.