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Riluzole is used to treat amyotrophic lateral sclerosis (ALS; Lou Gehrig's disease). Riluzole is in a class of medications called benzothiazoles. It works by changing the activity of certain natural substances in the body that affect nerves and muscles.
Riluzole is a medication used to treat amyotrophic lateral sclerosis and other motor neuron diseases. Riluzole delays the onset of ventilator-dependence or tracheostomy in some people and may increase survival by two to three months. Riluzole is available in tablet and liquid form.
- C₈H₅F₃N₂OS
- Rilutek, Tiglutik, Exservan, others
- AU: B3
Background. A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi. Type. Small Molecule. Groups. Approved, Investigational. Structure. 3D. Download. Similar Structures. Weight. Average: 234.198.
DrugInteractionThe risk or severity of CNS depression ...The serum concentration of Riluzole can ...The metabolism of Riluzole can be ...Abemaciclib may decrease the excretion ...15 de sept. de 2021 · How Riluzole (Rilutek) works. Riluzole (Rilutek) is a glutamate antagonist. It lowers the amount of a chemical called glutamate that's released in the body. We don't know what specifically causes ALS, but it's thought to involve nerve damage from high glutamate levels in the brain and spinal cord.
- Goodrx
1 de mar. de 2024 · Take it at least 1 hour before or 2 hours after meals. This medicine works best if there is a constant amount in the blood. To keep blood levels constant, take this medicine at the same time each day (eg, in the morning and in the evening) and do not miss any doses.
29 de may. de 2017 · Riluzole, a synthetic benzothiazole drug with glutamine antagonist activity, is indicated for the treatment of patients with ALS and is the only drug that has been shown to slow the course of the disease and extend survival in ALS patients.