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  1. Riluzole is used to treat amyotrophic lateral sclerosis (ALS; Lou Gehrig's disease). Riluzole is in a class of medications called benzothiazoles. It works by changing the activity of certain natural substances in the body that affect nerves and muscles.

  2. en.wikipedia.org › wiki › RiluzoleRiluzole - Wikipedia

    Riluzole. Riluzole is a medication used to treat amyotrophic lateral sclerosis and other motor neuron diseases. Riluzole delays the onset of ventilator -dependence or tracheostomy in some people and may increase survival by two to three months. [2] Riluzole is available in tablet and liquid form.

  3. Riluzole is a glutamate antagonist used to treat amyotrophic lateral sclerosis. Brand Names. Exservan, Rilutek, Tiglutik. Generic Name. Riluzole. DrugBank Accession Number. DB00740. Background. A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic ...

  4. This medicine works best if there is a constant amount in the blood. To keep blood levels constant, take this medicine at the same time each day (eg, in the morning and in the evening) and do not miss any doses. Dosing . The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label.

  5. 15 de sept. de 2021 · How Riluzole (Rilutek) works. Riluzole (Rilutek) is a glutamate antagonist.It lowers the amount of a chemical called glutamate that's released in the body. We don't know what specifically causes ALS, but it's thought to involve nerve damage from high glutamate levels in the brain and spinal cord.

  6. 29 de may. de 2017 · Riluzole use in the study was defined as use of riluzole for longer than 2 weeks (i.e., a cumulative defined daily dose [cDDD] of >1,400 mg based on DDD of 100 mg/d). Subgroups of patients were defined based on cDDD; the cDDD of 1 and 3 quartiles was 2,800 mg (about 1-month use) and 16,800 mg (about 6-month use), respectively.

  7. Descriptions. Riluzole is used to treat patients with amyotrophic lateral sclerosis (ALS), which is also known as Lou Gehrig's disease. Riluzole is not a cure for ALS, but it may extend survival for patients in the early stages of the disease or extend the time until a tracheostomy (breathing tube in the throat) is needed.