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Hace 3 días · We performed pathway analysis to reveal the biological role of the discovered non-invasive miRNAs in HNC by predicting miRNA targets and their interactions with the discovered mRNAs through cancer-related canonical pathways.
Hace 3 días · MicroRNAs (miRNAs) are small non-coding RNAs which contribute to the regulation of many physiological and pathological processes. Conventionally, miRNAs perform their activity in the cytoplasm where they regulate gene expression by interacting in a sequence-specific manner with mature messenger RNAs. Recent studies point to the presence of mature miRNAs in the nucleus. This review summarizes ...
Hace 2 días · The overlap between these target miRNAs and DEmiRNAs unveiled nine miRNAs that were both dysregulated in CRC and targets of hsa_circ_101303, forming distinct circRNA-miRNA pairs (Fig. 5 A).
Hace 4 días · MicroRNAs (miRNAs) and natural antisense transcripts (NATs) are two classes of regulators potentially involved in metabolism regulation. Here, we report the identification and characterization of 223 miRNAs and 363 miRNA targets. The identified miRNAs include 51 known miRNAs belonging to 20 families and 172 novel miRNAs belonging to ...
Hace 1 día · They facilitate the discovery of novel miRNAs, their targets, and their roles in plant biology. This knowledge has implications for improving crop yield, enhancing stress tolerance, and addressing various challenges in agriculture and plant science.
Hace 4 días · Through homology search-based computational techniques, we successfully identified 89 potential targets for the newly predicted miRNAs in muskmelon. The sequence features and characterization of the recently predicted conserved miRNAs are listed in (Table 2 ).
Hace 3 días · By intersecting the predicted DEmiRNA targets with the DEmRNAs identified through RNA-seq, we formed a final list of DEmiRNA-mRNA interactions.To construct the potential networks of DEcircRNA-DEmiRNA-DEmRNA interactions, we considered the shared miRNAs that were predicted as downstream targets of the DEcircRNAs and the upstream ...
