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  1. 28 de abr. de 2024 · Here, we develop and provide proof-of-concept evidence demonstrating a chemical G-clamp-enhanced photo-cross-linking strategy for covalent capture of intracellular miRNA targets in different cell lines.

  2. 14 de may. de 2024 · micro RNAs (miRNAs) are a type of non-coding RNA (ncRNA), ~21 24 nucleotides in length, that function in the post-transcriptional regulation of gene expression. Typically miRNAs interact with...

  3. 1 de may. de 2024 · MicroRNAs (miRNAs), a class of small noncoding RNAs approximately 22 nucleotides in length, are known to play fundamental roles in the regulation of gene expression.

  4. 24 de abr. de 2024 · Overall, this work presents insights into the role of miRNAs and fatty acid signalling in osteogenesis, providing future targets to improve bone formation and a promising system to enhance bone tissue engineering.

  5. 3 de may. de 2024 · As a major upstream regulator of the autophagic pathway, the mTOR-containing protein complexes and other proteins in this pathway are direct or indirect targets of many miRNAs. Vesicle...

  6. 2 de may. de 2024 · Circulating miRNAs have been developed as novel candidate non-invasive biomarkers for diagnosis, prognosis, and treatment response for diseases. However, miRNAs that have causal effects on Parkinson’s Disease (PD) remain largely unknown.

  7. 29 de abr. de 2024 · Researchers identified 93 miRNAs showing significant differential expression among healthy controls and adenoma and colorectal cancer groups. They computed ratios between these 93 miRNAs in all possible pairwise combinations, resulting in 2,529 ratios.