Resultado de búsqueda
Hace 1 día · IPA is an online software tool that provides a comprehensive data repository of information on genes, and miRNAs together with their experimentally validated and predicted interactions and biological functions. Gene targets were identified as either experimentally observed, predicted with high confidence, or predicted with moderate confidence.
Hace 4 días · The interplay between microRNAs (miRNAs) and phytohormones allows plants to integrate multiple internal and external signals to optimize their survival of different environmental conditions. Here, we report that miR394 and its target gene LEAF CURLING RESPONSIVENESS ( LCR ), which are transcriptionally responsive to BR, participate in BR signaling to regulate hypocotyl elongation in ...
Hace 4 días · Both miRNAs offer potential as biomarkers for early diagnosis and therapeutic targets for personalized treatment strategies in prostate cancer management (Luo et al. 2023a; Lu et al. 2021). The study by Gu et al. investigated the impact of hypoxia-responsive microRNAs on cellular metabolism and radioresistance in PCa (DU145 and PC3).
Hace 7 horas · Additionally, MSTRG.9645.5 predicted 88 target miRNAs, including six differentially expressed (DE) miRNAs. Moreover, the expression level of ame-miR-6057-5p (log 2 FC = 1.23, p < 0.05) was found to be significantly up-regulated in the high-temperature group and the expression level of novel-miR-53 (log 2 FC=-1.36, p < 0.05) was found to be significantly up-regulated.
Hace 7 horas · Small extracellular vesicle–derived microRNAs (sEV-miRNAs) have emerged as promising noninvasive biomarkers for early cancer diagnosis. Herein, we developed a molecular probe based on three-dimensional (3D) multiarmed DNA tetrahedral jumpers (mDNA-Js)-assisted DNAzyme activated by Na+, combined with a disposable paper-based electrode modified with a Zr-MOF–rGO–Au NP nanocomplex (ZrGA) to ...
Hace 2 días · To investigate the mechanism by which CAF-derived exosomes affect prostate cancer progression, an miRNA microarray assay was performed to identify differentially expressed miRNAs in exosomes ...
Hace 2 días · First, we mined miRNAs associated with the hub genes from the three databases of miRTarBase, Citation 34 DIANA-TarBase v8 Citation 38 and TargetScan, Citation 39 and intersected. Then, the obtained overlapping miRNAs were introduced into the starBase database Citation 40 for predicting of miRNA-lncRNA interactions.
